Vol. 3 No. 1 (2023)
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FORMULATION AND EVALUATION OF HERBAL MEDICATED BATH BOMB
Reetu, Himanshu Jaiswal, Kartikay PrakashArticle History: Submission:18.02.2023, Revision: 05.03.2023, Acceptance: 22.03.2023, DOI Information: https://doi.org/10.56815/IJMSCI.V3I1.2023/1- 9Abstract
OBJECTIVE: The field of cosmetic chemistry continually explores innovative products, one of which is the "Bath Bomb." This study aimed to formulate and evaluate a herbal medicated bath bomb designed to offer both therapeutic and cosmetic benefits such as relaxation, skin detoxification, and hydration. The bath bombs were developed using herbal ingredients like Neem, Tulsi, Rose, Lemongrass, and Honey, combined with sodium bicarbonate and citric acid, which act as key effervescent agents. Starch was employed to enhance the structural integrity of the bath bombs.
METHODS: The preparation method involved mixing the active ingredients through effervescence and diffusion techniques. Once formulated, the bath bombs were assessed based on their physical appearance, pH, effervescence time, and potential for skin irritation. Three formulations (F1, F2, and F3) were tested to compare their efficacy.
RESULT AND DISCUSSION: The results demonstrated that formulation F1 exhibited the most optimal performance, with a pH of 7.1 and an effervescence time of 30 seconds. It also passed the skin irritation test, proving it to be safe for topical use. All formulations showed good physical appearance, and none resulted in any skin irritation during testing. Formulation F1 had the most suitable balance of pH and effervescence time, making it superior to F2 and F3.
CONCLUSION: In conclusion, the development of a herbal medicated bath bomb was successful, and formulation F1 emerged as the most promising. This product holds potential in the cosmetic industry for offering a therapeutic, cost-effective bath experience
Keywords
Herbal bath bomb, Cosmetic chemistry, Effervescence, Natural ingredients, Therapeutic benefits,- pdf View and Download Full Article
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A COMPREHENSIVE REVIEW ON SUPERDISINTEGRANTS: ACCELERATING DISSOLUTION FOR ENHANCED DRUG PERFORMANCE
Lalita Tyagia, PriyanshubArticle History: Submission: 12.04. 2023, Revision: 23.04.2023, Acceptance: 10.05.2023, DOI Information: https://doi.org/10.56815/IJMSCI.V3I1.2023/10-27Abstract
To improve medication bioavailability and therapeutic efficacy, oral dosage forms must dissolve quickly and effectively. Drug release from solid formulations can be accelerated with the use of superdisintegrants, which are specialized chemicals that encourage disintegration. This study offers a thorough analysis of superdisintegrants, emphasizing their kinds, uses in pharmaceutical formulations, and modes of action. Superdisintegrants that speed up tablet breakdown, such as crospovidone, sodium starch glycolate, and croscarmellose sodium, enable quicker dissolving and absorption. Superdisintegrants are classified as natural, semi-synthetic, synthetic, and co-processed in the review, which also discusses their special qualities, benefits, and drawbacks. The physicochemical characteristics of the medicine and a number of other factors affect how well superdisintegrants promote disintegration. The drawbacks, such compatibility problems and possible impacts on medication stability, must be carefully considered despite their advantages. In addition, this review discusses current studies and potential directions for creating and using superdisintegrants for improved drug delivery systems. In order to facilitate the creation of high-performance medication formulations and enhance patient compliance and treatment results, this thorough review attempts to deepen our understanding of the roles and functions of superdisintegrants.
Keywords
Superdisintegrants, Drug dissolution, Croscarmellose sodium, Sodium starch glycolate, Crospovidone, Disintegration mechanisms, Synthetic superdisintegrants, Natural superdisintegrant, Semi-synthetic superdisintegrants, Disintegration,- pdf View and Download Full Article